Welcome
Welcome to the website of the Computational Toxicology Group. Here we publish the results of our research, offer free access to the toxicological databases and on-line toxicity prediction algorithms developed by the Group members.
Website is divided into two parts - open and accessible for registered users. To log in please create an account choosing Register new account link on your left hand side. Once the account is created we are starting the opening procedure which can take maximum few days. After that user has FULL, FREE access to the whole tox-portal.net content.
ToxComp stable version 1.1 launch!
It is our great pleasure to announce that the stable version 1.1 of the ToxComp platform has been launched. ToxComp specializes in in vitro - in vivo extrapolation of the drug triggered cardiotoxic effect and population analysis of such phenomenon. The latter one remains our main area of interest and new features allows for the detailed definition of the parameters influencing inter-individual variability to virtually mimic clinical trials. Detailed list of the new elements can be found in the Changelog.
To run the on-line version of the system or download version for off-line use please register/log-in and navigate to the ToxComp bookmark available in menu where you can also find list of new features in version 1.1. Detailed manual is accessible from the Repository after log in. We look forward to hear all your comments and queries!
CPW 2011 workshop materials become available
Lectures and materials presented during the 3rd International Workshop - Computational Pharmacy on-line workshop has been published and are now available for public and download.
ToxComp stable version 1.0 launch!
It is our great pleasure to announce that the stable version 1.0 of the ToxComp platform has been launched. ToxComp specializes in in vitro - in vivo extrapolation of the cardiotoxic effect and population analysis of such phenomenon.
To run the on-line version of the system or download version for off-line use please register/log-in and navigate to the ToxComp bookmark available in menu where you can also find list of new features in version 1.0. Detailed manual is accessible from the Repository. We look forward to hear all your comments and queries!
Berlin workshop materials become available
Materials presented and cases discussed during the 3rd Predicitive Toxicology meeting in Berlin are now available to download.
Beta version of the ToxComp platform goes on-line
It is our great pleasure to announce that the beta version of the Tox-Comp platform goes live. Tox-Comp specialize in in vitro - in vivo extrapolation of the cardiotoxic effect.
To run the system please log-in and navigate to the ToxComp bookmark available in menu. Detailed manual is accessible from the Repository. We look forward to hear all your comments and queries!
Major dataset upgrade
hERG channel inhibition potential database has been upgraded! Files (either .xlsx or .ods) are freely available in the tox-portal.net Repository - after registration. Largest publicly available set of data with triggered by drugs hERG inhibition information contains values expressed as IC50 for 263 molecules described in 642 records.
Results presentation
We will be presenting our results during the following conferences:
Mini-symposium Computational toxicology and pharmacology - in silico drug activity and safety assessment (Saturday, July 2, 11:00) during the 8-th European Conference on Mathematical and Theoretical Biology and Annual Meeting of The Society for Mathematical Biology; June 28 - July 2 2011; Krakow, Poland
MAJOR SYSTEM UPGRADE
New Year brings news to the Tox-Portal.net system. Under the Software link you will find free, system independent system designed for the hERG channel inhibition potential assessment. Extended hERG channel inhibition potential database is freely available in the tox-portal.net Repository - after registration. Files (either .xlsx or .ods) contain data gathered from available literature sources.
Supplementary materials for the conference presentation
hERG channel inhibition potential dataset used for the ANN based model development is now freely available in the tox-portal.net Repository - after registration. Files (either .xlsx or .ods) contain ready-to-use dataset.
Results will be presented during the 14th Online World Conference on Soft Computing in Industrial Applications (WSC14) - http://wsc14.science-city.org
New data files in the Repository
hERG channel inhibition potential database is now freely available in the tox-portal.net Repository - after registration. Files (either .xlsx or .ods) containing data gathered from available literature sources.
2nd CONFERENCE
2nd International Workshop - Computational Methods in Pharmaceutical Sciences will be organized in year 2010 in Gdansk, Poland as a part of the XXI Scientific Conference of the Polish Pharmaceutical Society. More detailes and registration form can be found at the official website (www.cpw.edu.pl). Stay updated - visit our webpages regularly!